| Place | Swimmer | Age | Club | Time | Std | Power pts |
|---|---|---|---|---|---|---|
| 1 | Derek Fan | 18 | OHBBA | 48.75 | AAAA | 842 |
| 2 | Owen Gee | 16 | OHCM | 50.84 | AAA | 775 |
| 3 | Charles Grisi | 18 | OHCM | 50.88 | AAA | 741 |
| 4 | Max Gao | 16 | OHCOA | 51.50 | AAA | 745 |
| 5 | Samyak Ramchandre | 16 | OHRAYS | 52.40 | AA | 707 |
| 6 | Ethan Tu | 18 | OHMAS | 52.76 | AA | 664 |
| 7 | Jonathan Malouf | 17 | OHCOA | 54.35 | A | 611 |
| 8 | Benjamin Oswiecinski | 16 | OHDCST | 54.90 | AA | 615 |
| 9 | Jacob Kreidler | 17 | OHDCO | 55.11 | A | 586 |
| 10 | Brendan Sulak | 17 | OHHVUS | 55.32 | A | 579 |
| 11 | Andersen Wozniak | 14 | OHBBA | 57.44 | A | 625 |
| 12 | Ethan Dong | 17 | OHBEA | 57.64 | BB | 512 |
| 1 | Ali Sadri | 16 | OHABLY | 57.68 | AAA | 710 |
| 13 | Brendan Ormiston | 17 | OHLSSC | 57.74 | BB | 510 |
| 14 | Brian Ormiston | 15 | OHLSSC | 57.83 | BB | 567 |
| 2 | Eva Hughes | 14 | OHBBA | 58.38 | AAA | 725 |
| 3 | Josephine Piliang | 16 | OHBBA | 59.57 | AA | 644 |
| 4 | Claire Liu | — | MAS | 1:01.15 | — | — |
| 5 | Lila Gregory | 17 | OHRAYS | 1:01.55 | A | 573 |
| 6 | Audrey Ehret | 16 | OHDCST | 1:01.81 | A | 577 |
| 7 | Adrianna DeVito | 16 | OHRAYS | 1:03.06 | A | 543 |
| 8 | Naomi Christianson | 16 | OHDCST | 1:04.24 | BB | 514 |
| 9 | Penelope Vrobel | — | SHHB | 1:05.62 | — | — |
| 10 | Amena Mitiek | 16 | OHLIFE | 1:05.89 | BB | 476 |
| 11 | Manuela Bernal-Viana | — | OHCHCA | 1:07.63 | — | — |
| 12 | Margaret Mussman | — | CSUA | 1:08.17 | — | — |
| 13 | Julia Molina | 14 | OHCHCA | 1:09.78 | BB | 425 |
| 14 | Blair Ryan | 16 | CSUA | 1:09.89 | B | 399 |